Abstract: Objectives: The aim of this study is to analyze the clinical features, laboratory findings and type of treatments in late onset SLE (after 50 years) in Iranian patients and compare them with the early onset. Methods: Records of 1419 SLE patients who attended our lupus unit, between 1975 and 1999 were reviewed. Nineteen Patients with late onset disease were identified. For comparison, 47 patients with disease onset before the age of ...
Abstract: INTRODUCTION : Ocular manifestations are one of the main features of Behcet’s Disease. They occur in more than half the patients. In our series they were seen in 58% of cases1. The natural course of Ocular manifestations, like other manifestations of Behcet's Disease, is a progression by repetitive attacks followed by remission. However, on the contrary of other lesions (muco-cutaneous) the remission is much slower in posterior uveitis, and practically absent ...
Abstract: Background: Our purpose was to show different aspects of the muco-cutaneous lesions of Behcet’s disease (BD). Although they are not specific, they constitute the major symptoms in all sets of diagnosis criteria for BD. Methods: Description of muco-cutaneous lesions seen during 12 years follow up in 4605 patients. Results: 1- Mucous-membrane lesions: Recurrent oral aphthosis (OA) is the most important and frequent lesion of BD. It resembles the other OA of other ...
Abstract: The chronic macular edema, frequent in ocular Behcet's disease, is a treat to the visual outcome of the patients. We have investigated the origin, risk-factors and the outcome of macular edema in patents under immunosuppressors and corticosteroid therapy. This is a retrospective, case series study. In 1999,seventeen patients of the Behcet's clinic of Shariati hospital of Tehran who had macular edema were consecutively selected and included in the study. They were ...
Abstract: Introduction: Ocular lesions of Behcet’s disease (BD) progress by recurrent attacks and remission. Their natural history, without treatment, is toward severe loss of vision or blindness. We presented last year a work to the ACR meeting on the long-term outcome of visual acuity (VA) in BD. The data showed that the final VA was related to the baseline VA (before the treatment), suggesting that a delay in aggressive treatment may ...
Abstract: Introduction: Pathergy test (PAT) is used in the majority of diagnosis criteria set for Behcet’s Disease (BD). The modality of performing it (needle gauge, sharpness of the tip, direction of skin penetration, with or without a product injection), the delay to read the result (24 or 48 hours), and the cut-off line for positive test is not standardized. Therefore the results differ from one center to another, introducing a great ...
Abstract: Introduction: It is known from long date that some manifestations are seen more frequently in men than women and in some of them the difference may be statistically significant. The aim of this study was to address that issue and to find if a statistical difference was of any clinical relevance or significance Materials and Methods: All patients of the BD registry (4717 at January 20, 2002) entered the ...
Abstract: Objective: Oral involvement is one of the most important manifestations in systemic sclerosis. We studied clinical and radiological presentations of patients with systemic sclerosis in IRAN. Methods: This study is a prospective case series on forty patients with systemic sclerosis (29 limited & 11 diffuse form) according to ACR (American College of Rheumatology) criteria, referred to Rheumatology Research Center from 2000-2001. For every patient, 41 data surveyed. Results: The mean age of ...
Abstract: Objectives: Behcet's disease (BD) is a multi-system disease. We present here the various clinical aspects of BD based on the data of 4586 Iranian patients. The male to female ratio was 1.17/l. The mean age at the onset of the disease was 26 yr (SD:9.6, CI:0.3). The mean disease duration was 9 yr (SD:7), and the mean follow up time was 3 yr (SD:3.8). As the first manifestation of the ...
Abstract: Pattern of Rheumatic Diseases in Iran: They have the same frequency and the same pattern as in Western countries. A study from 1993 demonstrated a prevalence of 32.6% among adults (31.4% in the USA, Cunningham 1984). Inflammatory disorders counted for 11% of all rheumatic diseases. The ratio of RA to AS was 8/1 (7/1 in USA), and SLE to Scleroderma 3.5/1 (3.6/1 in USA). Psoriatic arthritis and Reiter's syndrome were ...